Look at what we did in just one year – two new MOA targets and two high impact papers in Nature Magazine publications!

And we’re just getting started…

9 April 2025

Targeting POLG for rare and neurological conditions:
Small molecules restore mutant mitochondrial DNA polymerase activity

Read the paper here

 

30 April 2024

Targeting POLRMT for obesity and metabolic conditions:
Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity#

Read the paper here